Dr. Adam Sewell, MD breaks down inflammaging — the persistent, low-grade inflammation that accelerates degeneration across the body's systems — and what actually moves the needle on it.
Listen →Attia separates acute from chronic inflammation, works through which inflammatory markers are actually worth measuring versus which are noise, and what genuinely lowers chronic inflammatory burden. A practical counterpart to the mechanistic literature.
Listen →Three geroscientists (rheumatology, neurology, and critical care) map how chronic low-grade inflammation shows up across specialties — from rheumatologic disease to traumatic brain injury — and where the gap is between wellness-marketing claims and actual evidence on inflammaging tests and treatments.
Listen →Eric Verdin, CEO of the Buck Institute for Research on Aging, on how immune aging — thymic shrinkage, narrowing T-cell diversity, weaker vaccine response — acts as a rate-limiting step in aging, and how chronic inflammation is both a consequence and an accelerant of it. Also covers NAD decline and CD38, the real limits of NMN/NR/IV NAD, rapamycin, and what aging clocks can and can't tell you.
Listen →A condensed Huberman Lab episode with Rhonda Patrick on four micronutrients that influence cellular stress responses, inflammation, detoxification and longevity, and why common shortfalls in them may matter more than people assume.
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